Diagram illustrating the AI Evidence Integrity Lifecycle, consisting of four stages: Stage 1 - Early R&D/Pilot with the Governance Sprint; Stage 2 - Pre-Submission/GxP with Evidence Integrity Validation; Stage 3 - Production/Post-Market with Lifecycle Drift Assurance; and Stage 0 - The Principle 8 Gap Screen. An arrow titled 'Start with the Principle 8 Gap Screen' guides the flow. The diagram highlights a red ‘Black Box’ Stress Test at the center for rapid audit, connected by a GxP Transition Bridge. Each stage features specific activities and a guidance mapping.

The "Human-on-the-Loop" Governance Sprint 2–4 weeks

You can’t validate the model yet, but you must validate the interaction (Principle 8)

  • Context of Use Statement (Aligned to Principle 1)

  • Human-AI Interaction Rubric (Aligned to Principle 8)

  • Failure Mode Taxonomy (What happens when the agent hallucinates?)

Best For: Teams building "Agentic" workflows who need to prove they are in control before scaling.

Agentic Evidence Generation (Full Validation) 6–10 weeks

Move from 'Software Validation' to 'Evidence Integrity' (Principle 6). If the decision isn't traceable, it’s not evidence.

  • Decision Lineage Map (Traceability per Principle 6)

  • Model Credibility Plan (The new "Validation Plan")

  • Audit-Ready Evidence Pack

Best For: Clinical Ops, Safety, and Regulatory teams who need to defend the output to an auditor.

Lifecycle Drift Assurance (Principle 9 Service)

"Principle 9 mandates 'scheduled monitoring' for data drift. This is your regulatory insurance policy.

  • Quarterly Principle 9 Report (Documented proof of drift monitoring)

  • Change Control Impact Assessment (When they prompt-engineer a new version)

Best For: Organizations with LLMs in production

The GxP Bridge to AI Quality

Format: 5 Virtual Sessions (90 Mins Each) + Async Templates

Target Audience: Traditional QA/CSV Leads & Data Integrity Officers

The "Red Team" Inspection

A "Vulnerability Scorecard" showing exactly where the human-on-the-loop failed during a simulated hallucination.

Best for: Regulatory affairs teams preparing submissions; Quality/CSV/CSA teams doing inspection readiness; Clinical ops/CMC teams wanting a pre-inspection gap scan before QA review

The Principle 8 Gap Screen

In 20 minutes, I’ll tell you if your current human oversight strategy would pass a Principle 8 audit

No pitch. No pressure. Just clarity on whether this is the right path.

[Book a 20-minute fit check →]